Specificity and Catalytic Effectiveness of Enzymes

Non-competitive inhibitors bind to a part of the enzyme away from the active site and may also regulate an enzyme activity. Molecules that inhibit or activate enzyme activity may bind to an allosteric site, a receptor site separate from the active site. Allosteric enzymes may be critical regulators of metabolic pathways. Metabolic pathways are commonly regulated by feedback inhibition, in which the product of a pathway acts as an inhibitor of an enzyme early in the pathway.…